Objectives. The primary objective of this study is to evaluate the use of cinacalcet in the management of hyperparathyroidism in\nkidney transplant recipients. The secondary objective is to identify baseline factors that predict cinacalcet use after transplantation.\nMethods. In this single-center retrospective study, we conducted a chart review of all patients having been transplanted from 2003\nto 2012 and having received cinacalcet up to kidney transplantation and/or thereafter. Results. Twenty-seven patients were included\nwith a mean follow-up of 2.9 �± 2.4 years. Twenty-one were already taking cinacalcet at the time of transplantation. Cinacalcet was\nstopped within the first month in 12 of these patients of which 7 had to restart therapy.Themain reason for restarting cinacalcet was\nhypercalcemia. Length of treatment was 23 �± 26 months.There were only 3 cases of mild hypocalcemia. There was no statistically\nsignificant association between baseline factors and cinacalcet status a year later. Conclusions. Discontinuing cinacalcet within the\nfirst month of kidney transplantation often leads to hypercalcemia. Cinacalcet appears to be an effective treatment of hypercalcemic\nhyperparathyroidism in kidney transplant recipients. Further studies are needed to evaluate safety and long-term benefits.
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